Tylenol maker Kenvue denies the connection allegedly made in the report, which is expected to be published by the Department of Health and Human Services this month.
I’m confused where this zeitgeist about Tylenol being bad for you is coming from. I remember working in pharmacy that taking Acetaminophen was the least reactive painkiller with the least number of long-term issues, but I’m hearing a lot more people talking about how bad it is for you.
The studies I’ve seen have been correlative at best, and, considering that NSAIDs and opioid painkillers are far worse over time, I don’t understand the dissonance in advice that seems to be appearing.
It’s pretty easy to overdose on Acetaminophen, Wikipedia suggests >100k a year in the us (it’s in so many OTC medication, stuff like cough syrups and the like, really easy to hit the 4g/day max dose)
To add to this I’ve heard professionals in my field say if acetaminophen was discovered today it would likely be a controlled substance for this reason alone. The overdose potential is too high. That always seemed like an extreme measure but i can understand it.
I hope not, it’s apparently pretty awful. You were up to fairly recently able to get Acetaminophen w/ caffeine and codeine (8mg) over the counter in Canada, found an article about a decade ago that mentions liver injury in people, definitely recall reading articles about bans on the sale because of the injury risk.
Yeah I have been looking it up and it seems quite the opposite. aspirin and ibuprofen will irrate the stomach enough to make it hard to take to much but acetaminophen seems not to. Now I have no idea why they put acetaminophen with other meds. Its kinda funny because both my wife and I find acetaminophen to not really do much and prefer muscle relaxants. We also find opiods to not work all that well (like when its so bad from the surgery you can’t function they seem to be able to bring you to functional but to me don’t really get rid of the pain just sorta tamps it down) but the nerve ones like gapapentin were like. wow.
I don’t follow this topic regularly and I can’t say anything about the mechanisms. From a superficial search I would claim that there is good evidence that Tylenol use during pregnancy can make the development of asthma in the child more likely. There is also some indication (at least one large cohort study from Icahn medical school) that it may cause delayed language development.
That would be enough evidence for me to discourage use during pregnancy for treatment of discomfort or light pain, when safer options can be tried.
So what’s the deal with ibuprofen, naproxen, and aspirin? Seems every time the subject may come up with a doctor, they say ibuprofen to me (last time it came up was when I had to pass a kidney stone, and boy I think I could’ve used an opiate for that one time…).
Certainly a dramatic swing from 15 years ago when having a sonewhat sore throat during a physical landed me a prescription for opiate cough syrup…
NSAIDs cause crazy increased risk of intestinal bleeding and and it inhibits the ability for the kidneys to excrete uric acid, they also increase the risk of heart attack and stroke.
A lot of common over the counter drugs like Tylenol are more risky than people assume, so the idea of one having negative effects on fetal development isn’t out of left field. At the same time, not a single study pushed by this anti science ideologue can ever be trusted without corroboration by independent researchers. The risk of having a bad reaction to common medication nobody bats an eye at is often higher than the vaccines this dumbass rails against, so it’s not like a stopped clock being almost right makes up for his bullshit.
I’m confused where this zeitgeist about Tylenol being bad for you is coming from. I remember working in pharmacy that taking Acetaminophen was the least reactive painkiller with the least number of long-term issues, but I’m hearing a lot more people talking about how bad it is for you.
The studies I’ve seen have been correlative at best, and, considering that NSAIDs and opioid painkillers are far worse over time, I don’t understand the dissonance in advice that seems to be appearing.
Is this more “seed oil” nonsense?
It’s pretty easy to overdose on Acetaminophen, Wikipedia suggests >100k a year in the us (it’s in so many OTC medication, stuff like cough syrups and the like, really easy to hit the 4g/day max dose)
I’ll still use it, just use it responsibly.
To add to this I’ve heard professionals in my field say if acetaminophen was discovered today it would likely be a controlled substance for this reason alone. The overdose potential is too high. That always seemed like an extreme measure but i can understand it.
It’s more tightly controlled outside the US, in my experience. I think other heath agencies are quite aware of its risks
It’s not even a good pain reliever.
I don’t know why it’s so popular.
Ibuprofen/Motrin works about 100x better.
Just Fyi, paracetamol is acetaminophen.
FYI, Paracetamol = acetaminophen = Tylenol
Woops. Should’ve stuck to what I know.
I only heard the first two names myself.
all those drugs are the major source of liver failure.
People pop these like candy.
Isn’t Motrin the same drug but with caffeine added?
Moltrin and Ibuprofen are the same drug.
Excedrin is Ibuprofen with Caffeine.
I thought they put acetaminophen with other drugs to keep from overdosing because it will cause pain if you take to much.
I hope not, it’s apparently pretty awful. You were up to fairly recently able to get Acetaminophen w/ caffeine and codeine (8mg) over the counter in Canada, found an article about a decade ago that mentions liver injury in people, definitely recall reading articles about bans on the sale because of the injury risk.
Yeah I have been looking it up and it seems quite the opposite. aspirin and ibuprofen will irrate the stomach enough to make it hard to take to much but acetaminophen seems not to. Now I have no idea why they put acetaminophen with other meds. Its kinda funny because both my wife and I find acetaminophen to not really do much and prefer muscle relaxants. We also find opiods to not work all that well (like when its so bad from the surgery you can’t function they seem to be able to bring you to functional but to me don’t really get rid of the pain just sorta tamps it down) but the nerve ones like gapapentin were like. wow.
that’s why they sell coated versions.
Not as easy as aspirin.
I don’t follow this topic regularly and I can’t say anything about the mechanisms. From a superficial search I would claim that there is good evidence that Tylenol use during pregnancy can make the development of asthma in the child more likely. There is also some indication (at least one large cohort study from Icahn medical school) that it may cause delayed language development.
That would be enough evidence for me to discourage use during pregnancy for treatment of discomfort or light pain, when safer options can be tried.
My point is that comparatively, acetaminophen is (or at least was) the safest drug for light pain.
I haven’t seen any new categories of painkiller that would indicate that’s no longer the case, though.
So what’s the deal with ibuprofen, naproxen, and aspirin? Seems every time the subject may come up with a doctor, they say ibuprofen to me (last time it came up was when I had to pass a kidney stone, and boy I think I could’ve used an opiate for that one time…).
Certainly a dramatic swing from 15 years ago when having a sonewhat sore throat during a physical landed me a prescription for opiate cough syrup…
NSAIDs cause crazy increased risk of intestinal bleeding and and it inhibits the ability for the kidneys to excrete uric acid, they also increase the risk of heart attack and stroke.
A lot of common over the counter drugs like Tylenol are more risky than people assume, so the idea of one having negative effects on fetal development isn’t out of left field. At the same time, not a single study pushed by this anti science ideologue can ever be trusted without corroboration by independent researchers. The risk of having a bad reaction to common medication nobody bats an eye at is often higher than the vaccines this dumbass rails against, so it’s not like a stopped clock being almost right makes up for his bullshit.
Nice try, Jessica