I went through this a bit ago. The calibration of your pace is set during an outdoor run. Try and do one or two outdoor runs at the same pace as the treadmill and it should adjust.

Chezmoi has an amazing templating feature to address different files on different machines. It’s worth the time to set up.

You should only have to backup the Postgres database. But it won’t hurt to have a copy of your compose file as well.

This GitHub issue has the steps you should use. And answers all your other questions too.

Arch is great. You’ve kinda dipped your toes in it with Manjaro already. I recently moved to EndeavourOS with BTRFS for my gaming computer and couldn’t be happier. I could have done stock Arch but I honestly didn’t care enough to. EndeavourOS has great sane defaults and no bloat. And you can pick almost any DE during the install. Spin up a VM and give it a try if you can.

I can’t speak to MATLAB though. But all the others you mentioned I also run.

The only issue I have right now is the half screen flickering with GNOME and NVIDIA drivers. But I just ignore it.