The real curious thing is that these expected neurological rebound effects aren’t universally experienced. Some people are affected more strongly and in weird ways by withdrawal.
Being ADHD probably has something to do with it, but I can take my adderall (a relatively high dose btw) every day for months and then quit cold turkey and feel no noticeable withdrawal symptoms besides being hungrier and laughing at things more easily on the first few days after quitting lol
Now I’m wondering if there are neurodivergences for which GABA modulators cause different effects than expected and for which withdrawal symptoms might be negligible. Then again, GABA is like the major inhibitory neurotransmitter so maybe it’s not possible for the brain to function/develop well at all with any anomalies dealing with those receptors.
tbh I’m not on the research end I’m on the butt end with the people experiencing it directly (which is where I wanna be the most I wanna do is maybe teach someday) so I have empirical backup but most of my knowledge is experiential. I guess the best way I can describe it is that certain stuff just starts giving you anxiety. Nurse knowledge is like 2-3 years of following strict rules you learned in school then when you hit your stride something crystallizes in your brain and you can just look at certain patients through that lens and your nervous system just says “absofuckinglutely not, no.” So I can’t cite stats I can just tell you where the needle is on how anxious it makes me. Which is it’s own type of knowledge.
The real curious thing is that these expected neurological rebound effects aren’t universally experienced. Some people are affected more strongly and in weird ways by withdrawal.
Being ADHD probably has something to do with it, but I can take my adderall (a relatively high dose btw) every day for months and then quit cold turkey and feel no noticeable withdrawal symptoms besides being hungrier and laughing at things more easily on the first few days after quitting lol
Now I’m wondering if there are neurodivergences for which GABA modulators cause different effects than expected and for which withdrawal symptoms might be negligible. Then again, GABA is like the major inhibitory neurotransmitter so maybe it’s not possible for the brain to function/develop well at all with any anomalies dealing with those receptors.
(This is not my field; I’m just curious.)
tbh I’m not on the research end I’m on the butt end with the people experiencing it directly (which is where I wanna be the most I wanna do is maybe teach someday) so I have empirical backup but most of my knowledge is experiential. I guess the best way I can describe it is that certain stuff just starts giving you anxiety. Nurse knowledge is like 2-3 years of following strict rules you learned in school then when you hit your stride something crystallizes in your brain and you can just look at certain patients through that lens and your nervous system just says “absofuckinglutely not, no.” So I can’t cite stats I can just tell you where the needle is on how anxious it makes me. Which is it’s own type of knowledge.