Neat, thanks for the clarification. Even though the initial proportion is 50/50 for X-activation, are there scenarios where one daughter line is more prominent than the other, or does it usually remain 50/50?
Statistics would indicate that that is a plausible scenario.
In addition, a uniparental disomy can occur as well. Here, the X chromosome was duplicated in the egg cell. So the exact same X chromosome is inherited twice.This is an error in meiosis. This could occur in XXX (with the third X from the father’s side), XXY, or even XX. That latter one would be rare, for a uniparental disomy on X without a third sex chromosome would mean both egg and sperm cell had an error during meiosis.
You could also see a single X (Turner Syndrome) as a 100% dominant X-chromosome. But that may be semantics.
Neat, thanks for the clarification. Even though the initial proportion is 50/50 for X-activation, are there scenarios where one daughter line is more prominent than the other, or does it usually remain 50/50?
Statistics would indicate that that is a plausible scenario.
In addition, a uniparental disomy can occur as well. Here, the X chromosome was duplicated in the egg cell. So the exact same X chromosome is inherited twice.This is an error in meiosis. This could occur in XXX (with the third X from the father’s side), XXY, or even XX. That latter one would be rare, for a uniparental disomy on X without a third sex chromosome would mean both egg and sperm cell had an error during meiosis.
You could also see a single X (Turner Syndrome) as a 100% dominant X-chromosome. But that may be semantics.