Salamander

  • 6 Posts
  • 206 Comments
Joined 4 years ago
cake
Cake day: December 19th, 2021

help-circle





  • I would take a portable CD player, place a CD with Rick Astley’s Never Gonna Give You Up on it playing backwards, hook up solar panels, remove the ability to shut it on/off, and set it up a circuit that will:

    • As the device solar charges, keep it off until some voltage threshold is exceeded
    • Once the voltage is high enough, start a random timer (8 - 100 hours), so that it is not immediately obvious that the sun activated the device
    • When the timer ends, turn the music on on repeat mode
    • Sometimes turn the music off at random, and then turn it on again at random after a long delay, so that in some cases you can have turn ‘ON’ events without the device being exposed to the sun
    • When the voltage drops below a low threshold, turn the device off until it is charged again

  • I speak spanish natively and at during uni I would hang out with a group of Brazillian friends. I would speak a mixture of portuguese and spanish with them.

    The mom of one of these friends made a Brazilian dish for us (Feijoada) and asked me how it was as it was the first time I tried it. I answered that the dish as ‘exquisito’, which in Spanish means delicious (similar ‘exquisite’). She seemed somewhat disappointed and upset by my response so I probed a little and found out that ‘esquisito’ in Portuguese actually means ‘weird’. She thought I was calling her dish weird tasting. I found quickly enough to clarify, but I did feel bad about making her fell that way… She was very excited about sharing her cooking and she thought I called it weird.


  • The use-cases that I see advertised are not things that I do in my day-to-day. I usually place my phone on a drawer or leave it in my backpack - I definitely don’t want it on my face.

    So, to me, smart glasses feel like an uncomfortable gimmick at this point. Maybe there is something amazing about them that has not yet clicked with me, but for the time being I don’t see me buying one of these for the foreseeable future.


  • I also did not know of him at all. I did know who Ben Shapiro is. This week has been an educational one: I have learned about Nick Fuentes and ‘groypers’, Candace Owens, and that the change my mind meme guy is called Steven Crowder (I first thought it was this guy when I saw the video of Kirk).

    The US political commentator that I do watch some times is Hasan, but not too often. The US lore goes too deep and moves too quickly, hard to keep up.






  • Some of these ‘games’ do trigger real physiological mechanisms. A well-documented example is the Valsalva maneuver, where forcefully exhaling against a closed mouth and nose affects heart rate and blood pressure.

    In some games, this maneuver (or similar) is combined with a second action that normally increases blood flow demand to the brain. The mismatch between reduced blood pressure and sudden demand can cause dizziness or brief loss of consciousness due to insufficient oxygen reaching the brain.

    Actually, there is a similar effect sometimes seen during heavy deadlifts, suddenly releasing can sometimes make people pass out. There are many “deadlift passing out” videos online.

    So, those ‘games’ can work. I have known of kids breaking their teeth after face-planting against the floor while playing those games. Not a very smart thing to do.


  • If you catch a frog in between your hands and quickly flip it around, you can get the frog into a kind of paralyzed state called ‘tonic immobility’.

    Here is a photo from Wikipedia:

    Frog stuck in tonic immobility

    OK, well, many years ago I was very interested in this phenomenon and decided to look into the literature.

    I found a paper from 1928 titled “On The Mechanism of Tonic Immobility in Vertebrates” written by Hudson Hoagland (PDF link).

    In this paper, the author describes contraptions he used to flip animals quickly and get them into this state. They look kind of like torture devices:

    OK, but, that’s still not it… The obscure fact is found in the first footnote of that paper, on page #2:

    Tonic immobility or a state akin to it has been described in children by Pieron
(1913). I have recently been able to produce the condition in adult human beings.
The technique was brought to my attention by a student in physiology, Mr. W. I.
Gregg, who after hearing a lecture on tonic immobility suggested that a state
produced by the following form of manhandling which he had seen exhibited as a
sort of trick might be essentially the same thing. If one bends forward from the
waist through an angle of 90°, places the hands on the abdomen, and after taking a
deep breath is violently thrown backwards through 180° by a man on either side,
the skeletal muscles contract vigorously and a state of pronounced immobility
lasting for some seconds may result. The condition is striking and of especial
interest since this type of manipulation (sudden turning into a dorsal position) is
the most common one used for producing tonic immobility in vertebrates.

    Apparently this or a similar effect can be observed in humans too?! In this paper, the author himself claims to have done this and that it works! I tried to locate more recent resources describing this phenomenon in humans but I could not find them… Is this actually possible? If so, why is this not better documented? Or, maybe it is better documented but understood as a different type of reflex today? Not sure.




  • EDIT: After reading through the Git issue and the other comments in this thread, it is not very clear to me what “combining comments from cross-posts on the post screen” means. I understood it at first to mean that you will pool all comments together and show all of them in all cross-posts, but now I am not so sure. Still, in general terms, I think that mechanisms to share activity with niche communities are good

    I would say yes, there are cases in which I have thought that this would be a nice thing to have. Especially when cross-posting to a smaller niche community.

    I can think of a few potential small issues. For example, cross-posters can edit the body of the message, so you might in some cases end up with comments that seem out of place as they refer to the content specific to a cross-post. You also have the rare case in which the same post might mean different things in different communities.

    But, overall, I see it as beneficial. Quirks can be fine-tuned later on.


  • Fair point - I completely forgot to take the 3D geometry into account. I guess this could be solved by either making both sp³ (sub the Si-O with Si-Cl) or both sp² (sub the H-O-Si with H-N=Si)? But then writing data becomes more complicated than just adding or removing hydrogens that, as you said, isn’t as simple as it looks like.

    I think that the solution that life came up with - making a flexible double helix-forming backbone from which base pairs hang is actually a pretty good way of going about it. Similar as with proteins - a standard flexible backbone with different groups hanging off the chain and influencing how it folds. In your proposition you have the silicon backbone and a single atom as the ‘side chain’, so there is no separation between the backbone and the pairing elements to add this flexibility.

    There are also some other details to consider. For example, the amount of data you can store in a given chain length changes depending on how many different types of chemistry you have. In your example, you are using only one type of ‘base’ because the only options are ‘hydrogen bond donor’ or ‘hydrogen bond acceptor’. If you have a chain length of 3, you get only 3 bits, which can store one of 2^3 = 8 values from 0 to 7 (000 to 111). With DNA, you have 4 different base pairs, so a chain length of three can encode 4^3 = 64 values.

    That means that, to get a good information density, you would also want to increase the number of possibilities. The challenge here is that you need to tune the set of possibilities so that the thermodynamics are balanced. You don’t want some pairs to stick very strongly while others stick only loosely, and you also don’t want certain bases to be able to pair with each other. See: https://en.wikipedia.org/wiki/Nucleic_acid_thermodynamics

    You can perhaps dispense with some of the thermodynamic tuning if you don’t need to be able to easily replicate the data through a process similar to DNA replication, as you don’t actually need to ‘pair’ at all - you have a single string of data. But in that case you lose a very powerful method as you are forced to re-synthesize every data chain from scratch - I think that with such a system you lose too many benefits.

    If you go through the steps of creating a system of molecular data storage from scratch, I think it is easy to converge towards something similar to DNA. A lot of ‘origin of life’ research is actually about this - thinking about these systems and how to engineer them from scratch, and… DNA is pretty good at this. When you consider that early chemical evolution was an optimization algorithm to solve this problem, it makes sense that DNA is a good choice.

    I do think it is good and fun to explore this. We do have at least some advantages over nature - for example, we have managed to purify many compounds that were not abundant in early chemical soups. So, perhaps we can find something.

    Like the dNaM / dTPT3 pair, right? That’s perhaps more viable, at least to increase information density.

    Yeah, like those. In this recent paper, for example, researchers sequenced a chain of four anthrophogenic base pairs that they refer to as ‘ALIEN bases’: https://www.nature.com/articles/s41467-025-61991-9


  • The R2S=O case is closer to a trigonal planar geometry, the other silicon is tetrahedral. The silicon-silicon distances for different pairs of adjacent molecule types will be different. In a very very rough forcefield optimization I see about 3% difference. I don’t think this one will work out structurally because the chains will become unable to pair after a short length as the chain will not have the flexibility to create the O–H bond without adding too much strain.

    But, that’s just one thing. You then need to consider how to actually selectively place/remove the hydrogen atoms, how to avoid the molecule from chemically reacting, and how to read out the data.

    So, yes, eventually it would be nice to have a fully orthogonal system. There are already several synthetic DNA base pairs that can be used instead of the naturally present bases. But these would still be susceptible to DNAses or RNAses.

    The way I see it is that the chemistry of living things is currently centuries ahead of human tech. A large portion of the techniques used in biochemistry rely on using living things to produce the components, and then we purify those components and use them. It makes a lot of sense to make use of that toolkit because the amount of challenges that need to be solved to create this system from scratch is massive.

    Your proposal of your silicon chain reminds of the Ferroelectric RAM, where the state is encoded by the polarity of a cell that is changed by moving a zirconium or titanium cation:

    This does work, but it works because the crystal is contained within a semiconductor scaffold, and this is something that we do have a good handle on.